AmphaSoft pro

Software for Structured Cell Data Evaluation

Integrated analysis environment for reproducible interpretation of impedance-based cell measurements

Impedance flow cytometry generates quantitative measurements of cell populations on single-cell level. Furthermore, the integrated Amphasys software converts these electrical signals into data, enabling both rapid, routine analysis and in-depth analysis of complex research tasks for better insights into cell viability and process performance in bioprocessing.

As a result, the sophisticated software enables user-friendly operation with intuitive menus – for reliable interpretation of your data.

From Electrical Measurement to Interpretable Output

Specifically, each cell generates an electrical signal during measurement which includes information about size, membrane integrity, and cytoplasmic conductivity. Then, the software processes these signals into single dots of a two-dimensional scatterplot.

This enables:

  • Classification of viable and non-viable cell fractions
  • Visualization of cell population structure
  • Quantitative comparison between samples
  • Generation of standardized result outputs

Overall, the software enables both fully automated data analysis and detailed individual interpretation.

Designed for Routine Laboratory Operation

The software environment is purpose-built to transform single-cell impedance signals into meaningful information.

In particular, in bioprocessing it supports:

  • Standardized evaluation settings
  • Defined classification logic
  • Consistent data processing workflows
  • Clear graphical representation of population data

Consequently, the interface supports routine laboratory use without requiring advanced cytometry expertise.

Reproducibility and Comparability

Importantly, measurements for analyzing cell viability and process performance are only meaningful if they are reproducible and comparable.

Therefore, the software supports standardization through:

  • Application of uniform evaluation parameters
  • Elimination of operator-dependent variability
  • Enabling the comparison across samples
  • Providing structured documentation of results

As a result, this ensures that you can use cell viability data reliably and comparably for location- and user-independent analyses.

Integrated Component of the Measurement System

The Amphasys instrument platform includes the software and operates directly in alignment with the defined measurement configurations.

Moreover, you do not need any additional software infrastructure. The system fully integrates data analysis with the impedance measurement workflow.

Ampha X30

Label-free cell analysis for efficient bioprocessing

The Ampha X30 provides real-time, multiparametric analysis of cell properties in bioprocessing, cell culture monitoring and for detailed single-cell analysis in academic research.

Key benefits:

  • Label-free, impedance-based single-cell analysis
  • Fast measurements for cell culture monitoring and screening
  • Reproducible, reliable data for upstream  bioprocess development
  • Suitable for both R&D workflows and routine quality control
  • GMP-ready

The Ampha X30 serves as a versatile platform for counting, analyzing cell viability and metabolic status in a label-free way, providing real-time data in single-cell resolution.

AmphaChip

AmphaChip for highest sensitivity and performance

Amphasys offers two kinds of measurement chips: universal AmphaChips with different channel dimensions to accommodate varying cell sizes and application-specific chips designated for defined cell types featuring automated data analysis.

  • Label-free analysis in single cell resolution
  • In-depth analysis of cell count, viability, and metabolic state
  • Reliable measurement of bacteria and other small cells
  • Reliable measurements of cells in low concentration
  • Guaranteed 1000 measurement per chip for low operational costs

Both universal and application-specific AmphaChips offer high sensitivity and high throughput for all cell analysis tasks, from research to routine quality control and process development.

Frequently Asked Questions

Does the software require prior flow cytometry experience?

No. The analysis workflow is specifically designed for cell analysis and does not require any special knowledge of flow cytometry. Experience with gating scatter plots is advantageous, but not essential.

Can raw data be accessed?

Yes. Measurement data can be reviewed and exported for further documentation or advanced analysis.

 

Are evaluation settings consistent across instruments?

Yes. Defined parameter configurations ensure consistent classification and comparability across systems.

Explore your application with Amphasys

Ready to improve your bioprocess efficiency or cell analysis accuracy? Our experts are here to help you find the right solution for your specific needs.